Biopsies

Biopsies in oral surgery involve removing a small tissue sample from suspicious lesions or abnormalities in the oral cavity for microscopic examination. This diagnostic procedure aims to determine the nature of the abnormality, such as the presence of cancerous or precancerous cells, inflammatory changes, or infections.

Biopsies are critical for early detection, accurate diagnosis, and subsequent treatment planning for various oral diseases, including oral cancer. By providing essential diagnostic information, biopsies enable timely intervention and appropriate management, ultimately contributing to better patient outcomes and improved oral health.

The Dental Biopsy Procedure 

The dental biopsy procedure is critical in diagnosing oral health conditions, requiring careful planning and execution. The process begins with a comprehensive pre-procedure assessment. This involves assessing the patient’s detailed medical and dental history to identify underlying conditions that might affect the biopsy.

A thorough clinical examination of the lesion is often supplemented with imaging studies like X-rays,  MRI , or  CT   scans to assess the lesion's size, location, and extent. This information helps the dentist or oral surgeon determine the most appropriate type of biopsy and plan the procedure accordingly. 

Once the pre-assessment is complete, the next step is administering anesthesia to ensure patient comfort. Local anesthesia is commonly used to numb the area around the lesion. In some cases, particularly for more extensive or invasive procedures, sedation might help the patient relax.

The choice of anesthesia depends on factors such as the patient's medical history, the lesion's nature, and the biopsy's complexity. With the area adequately anesthetized, the dentist proceeds with the biopsy, which can be an incisional, excisional, punch, or needle biopsy, depending on the specific circumstances. 

During an incisional biopsy, the dentist removes a small portion of the lesion and some surrounding normal tissue using a scalpel. This method is chosen when the lesion is too large to remove entirely or when a small sample is sufficient for diagnosis. An excisional biopsy removes the entire lesion, which might involve more extensive cutting and suturing.

Punch biopsies are performed using a circular blade to extract a cylindrical tissue core, which is ideal for flat or slightly raised lesions. Needle biopsies, including fine-needle aspiration (FNA) and core needle biopsy, involve inserting a needle to withdraw tissue or fluid from deeper lesions. Throughout the procedure, sterile techniques are used to minimize the risk of infection.

After it is obtained, the tissue sample is preserved in an appropriate medium and sent to a pathology lab for microscopic examination. The biopsy site is then managed to promote healing. This may include suturing the area, applying pressure to control bleeding, and providing the patient with detailed post-procedure care instructions.

Patients are advised to maintain oral hygiene, manage pain with prescribed medications, and modify their diet to avoid irritating the biopsy site. Follow-up appointments are scheduled to monitor the healing process and to discuss the biopsy results with the patient. 

The final step in the biopsy procedure involves analyzing the tissue sample at the pathology lab. The results, typically available within a few days to a week, provide crucial information about the nature of the lesion. These results guide further patient management, including additional diagnostic tests, treatment planning, or referral to a specialist if necessary.

Clear communication of the biopsy findings and their implications is essential to ensure the patient understands their condition and complies with the recommended treatment plan. This comprehensive approach to the dental biopsy procedure ensures accurate diagnosis and optimal patient care. Contact us today to learn more! 

Types of Dental Biopsies 

Incisional Biopsy 

  • Involves removing a small part of a lesion
  • Used when the lesion is large or appears suspicious but not definitively diagnosable by other means
  • Typically performed when malignancy is suspected 

Excisional Biopsy 

  • Removes the entire lesion 
  • Preferred for small, accessible lesions 
  • Often used for therapeutic purposes as well as diagnostic, especially for benign lesions 

Punch Biopsy 

  • Performed using a circular blade to remove a small, cylindrical section of tissue 
  • Commonly used for lesions on the mucosa or skin 

Needle Biopsy 

  • Involves the use of a needle to extract tissue or fluid  
  • Fine-needle aspiration (FNA) is a type of needle biopsy that extracts cells for cytological examination  
  • Less invasive and often used for deeper lesions

Indications for Dental Biopsies 

Dental biopsies are essential for diagnosing various conditions within the oral cavity.

Suspicious Lesions

One of the primary indications for a dental biopsy is the presence of suspicious lesions. Lesions that persist for more than two weeks despite initial treatment efforts or present with unusual characteristics, such as irregular borders, rapid growth, non-healing sores, or changes in color and texture, require a biopsy to rule out malignancy. White patches (leukoplakia), red patches (erythroplakia), and mixed red and white lesions often warrant further investigation through biopsy due to their potential for malignant transformation.

Oral Cancer

Another critical indication for dental biopsies is for the detection of oral cancer. Early identification of potentially malignant conditions significantly improves patient prognosis. Biopsies help in the early detection of oral squamous cell carcinoma and other malignancies, enabling timely intervention.

Inflammatory Conditions

Chronic inflammatory conditions such as lichen planus, pemphigus vulgaris, and mucous membrane pemphigoid may necessitate a biopsy for definitive diagnosis. These conditions often present with persistent ulcerations or erosions in the oral mucosa that do not respond to standard treatments.

Cysts and Tumors

Dental biopsies are also indicated for evaluating cysts and tumors within the oral cavity. Any growth or swelling, whether symptomatic or asymptomatic, that appears suspicious or has been present for an extended period should be biopsied to differentiate between benign and malignant pathology. This is particularly important for proliferative lesions that have recurred after previous treatment.

Systemic Conditions

Furthermore, systemic diseases with oral manifestations, such as Sjögren's syndrome, may require salivary gland biopsy for diagnosis. This helps confirm systemic conditions affecting the oral cavity, guiding appropriate management and treatment strategies.

Biopsies are indispensable in dentistry, enabling dentists to effectively diagnose and manage a wide range of oral conditions. Visit Ali Haeri D.M.D., M.H.S. at 1297 W Main St., Suite A, El Cajon, CA 92020-4135, or call (619) 579-0505 to learn more.

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